Planova™ BioEX

Durable membrane material

Planova™ BioEX image02

Developed using Asahi Kasei’s world-leading technologies of hollow fiber virus removal filters and polymer science, Planova™ BioEX filters incorporate durable hydrophilic modified polyvinylidene fluoride (PVDF) hollow fiber membranes. The membranes are specially designed to meet a critical need in downstream biopharmaceutical processing for robust virus filters which exhibit enhanced pathogen safety, higher filtration capacities and shorter processing times even under harsh conditions. With Planova™ BioEX filters, users are able to efficiently filter large volumes of high protein concentration solutions, which are typically problematic for traditional types of virus removal filters, particularly those with flat-sheet membranes.

Filter structure

Like Planova™ 15N, 20N, 35N and 75N filters, Planova™ BioEX filter also contains a bundle of straw-shaped hollow fibers. The wall of each hollow fiber has a three-dimensional web structure of pores comprised of voids interconnected by fine capillaries.

Filtration mechanism

Planova™ BioEX image03

Based on size exclusion mechanism, membrane structure of Planova™ BioEX allows proteins to easily pass through the hollow fiber walls while viruses are efficiently captured in these pores. During filtration of protein solutions, viruses are effectively removed yet proteins smoothly permeate the membrane, resulting in high protein recovery rates without adsorption or denaturation.

contact us

Please make sure to have cookies activated before login!

E-mail address
Password
  •  Workshop 2017 - Plague
  •  Workshop 2018 - SanFrancisco
  •  Web Survey - 2017
Top of page