BioOptimal™ MF-SL

Quick large volume processing

A key feature of BioOptimal™ MF-SL is its ability to quickly process large volumes of feed solution. As shown in the figure on the right, compared to other existing microfilters, BioOptimal™ MF-SL can process the largest volume of solution in the shortest amount of time.

Filtration Volume vs. Filtration Time

Filtration Volume vs. Filtration Time Graph

Experiment processed a suspension of CHO cells with Cell Density: 1.2x107 cells/mL, Viability: 99.4%, Turbidity: 872 NTU

Stable filtration performance

Unlike other microfilters, BioOptimal™ MF-SL's unique membrane structure and tangential flow filtration mode allow it to provide a consistently low TMP despite increases in filtration volume.
This low TMP results in a reliably high target protein recovery rate.

TMP vs. Filtration Time

TMP vs. Filtration Time Graph

Experiment processed a suspension of CHO cells with Cell Density: 1.2x107 cells/mL, Viability: 99.4%, Turbidity: 872 NTU

High protein recovery rate

BioOptimal™ MF-SL achieves high recovery rates of target proteins. The figure on right, which illustrates the before and after of a BioOptimal™ MF-SL filtration, shows a filtrate with a 92% recovery rate of the IgG originally spiked into the CHO cell feed solution.

IgG Quantity Before and After Filtration

IgG Quantity Before and After Filtration Graph
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